Multi-system, multi-symptom illness
Chronic Fatigue Syndrome (CFS)
CFS is also known as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Definition
The cause of CFS is unknown. There have been many proposed etiologies. The main causes studied are infections, immune and endocrine dysfunction, and neuropsychiatric factors.
Signs & Symptoms
Symptoms should be present for at least 6 months and have moderate to severe intensity for at least half of the time. Symptoms include:
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Fatigue
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Post-exertional malaise
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Unrefreshing sleep
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Cognitive impairment
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Orthostatic-related symptoms
CIRS is a condition that can share many similar signs and symptoms and should be ruled out as a cause of CFS.